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PROGEN HEALTHY
Melatonin Sleep Spray
Water-Soluble Melatonin Improves Sleep：Sleep And Health
- Safe
- Water-soluble
- Sleep Aid
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Direct Health Impacts of Low-Quality Sleep
The existence of sleep disturbances brings about
"secondary harm,"affecting not only the appearance but also having negative impacts on mental health,physical well-being,work,and daly life.Poor sleep can increase the risk of various diseases, such as heart disease,breast cancer,and urinary
issues.Therefore,getting a good night's sleep is the first step toward maintaining a healthy body.
Decreased Appearance
Loss of face value
Overworked and fat 9%
Decline in appearance level 19%
Vision loss 30%
Drowsiness
Drowsiness and dozing off 45%
Dazed 33%
Listlessness 40%
Striking Out
Inattentive 47%
Inefficiency 34%
Lack of inspiration 17%
Exhausted
Immunity weakened 37%
Moodiness 33%
Physical discomfort 29%
Sleep Is An Important Line of Defense For Human Immunity
A good night's sleep strengthens the body's immune systemto a large extent and protects the body's health.
- 01
Relationship between sleep and colds
Duration of sleep:<7 hours of sleep is associated with a 3-fold increased risk of colds compared to >8 hours
Duration of sleep:>30 minutes of sleep is associated with a 5-fold increased risk of colds compared to <15minutes of sleep
- 02
The relationship between sleep and human immune cells
T-lymphocytes and B-lymphocytes are the mainstay of immune function in the human body.
A team of Prof.Darby from Florida, USA, found that T- and B-cells in the human body are significantly increased after sleep compared to those before sleep, which proves the positive impact of sleep on immunity and health.
Dangers Of Chronic Insomnia: Increased Risk Of Disease
Poor sleep can lead to an increased risk of various diseases, such as heart disease, breast cancer, urinary problems,etc., so a good night's sleep is the first step to a healthy body.
Risk Of Heart Disease
Researchers at the West Virginia University School of Medicine found that those who sleep less than seven hours a night have an increased risk of heart disease.
Risk Of Breast Cancer
Scholars at the Tohoku University Graduate School of Medicine in Japan found that women who sleep less than six hours a night have a 62% higher risk of breastcancer.
Urinary System Problems
The American Urological Association found that within five years of poor sleep, or sleep deprivation women's risk of getting up in the night (enuresis) or urinaryincontinence will increase by 80 to 90 percent.Researchers hypothesized that sleep deprivationcauses inflammation, which can lead to a number of urinary problems.
Risk of Colorectal Polyps
Researchers at Case Western University found that among 1,240 subjects, those who slept fewer than six hours a night had a 47 percent higher risk of colorectal polyps than those who slept at least seven hours.
Risk of Die
Men who slept poorly, especially those under 45, were twice as likely to die as men who slept well.
What Is Melatonin?
* Melatonin,a hormone produced in the pineal gland,is also found in plants and microbes,and is mainly
associated with circadian rhythm regulation.* Melatonin receptors are scattered throughout the body, participating in the control of many physiological
processes,and playing anti-oxidation,anti-nflamma- tion,anti-cancer and other functions.* Factors such as irregular schedules, excessive screen exposure, stress, jet lag, and aging can reduce natural melatonin production, leading to difficulty falling asleep and poor sleep quality.
PROGEN Melatonin Sleep Spray is designed to support individuals who experience difficulty falling asleep.
PROGEN Melatonin Sleep Spray is designed to support individuals who experience difficulty falling asleep.
No Need To Take Orally
Reduced Side Effects
Greater Safety
PROGEN-Water-Soluble Melatonin Improves Sleep
By introducing sodium sulfonate onto the melatonin
structure through chemical synthesis,the water
solubility of the molecule is increased nearly 1000-fold.The oral bioavailability of melatonin is extremely low,with plasma concentrations returning to baseline levels
approximately 3-4 hours later. The low retention time in the
body fails to achieve the desired effect.
No Need To Take Orally
Reduced Side Effects
Greater Safety
- Address The Issue Of Low Water Solubility：
Solubility limitations affect various fields such as agriculture, cosmetics,and mechanistic research. - Solve The Problem Of Low Bioavailability：
High lipophilicity allows for rapid passage through the blood-brain barrier,but the retention time in the blood is short. - Overcome The Challenge Of High Development Dificulty：
Natural melatonin molecules lack effective active modifica- tion sites,making it impossible to further study derivatives.
PROGEN Melatonin Sleep Spray
Administered In The Form Of A Spray. It Is Absorbed Through The Skin to Exert Its Sleep-Aiding Effects
Key Functions & Benefits
The Melatonin Sleep Spray is an innovative sleep-support solution administered in a convenient spray form. Designed for fast and effective delivery, the spray allows melatonin to be absorbed through the skin, enabling efficient uptake into the body to support the natural sleep cycle.
By bypassing the digestive system, this transdermal absorption method helps achieve quicker onset and improved bioavailability compared to traditional oral supplements. The formula is developed to assist in regulating circadian rhythm, promoting relaxation, reducing sleep onset time, and improving overall sleep quality.
This spray-based delivery system offers a non-invasive, easy-to-use alternative for individuals seeking gentle and effective sleep support, particularly for those sensitive to pills or capsules.
GO TO BED EARLY
Fall asleep before 11PM
ADEQUATE SLEEP
Get enough sleep 8 hours
DEEP SLEEP
Have leisure time
SIESTA
Have leisure time
Take a short nap during the afternoon
R&D Customization
Melatonin Sleep Spray Solutions for Modern Wellness Brands
At PROGEN, we offer professional R&D and formulation customization services for melatonin sleep sprays and wellness products.
Whether you are building a new brand or expanding your product line, our team supports you from concept development to formulation optimization and production readiness.
Contact us today to discuss your customized sleep support solution.